Density-dependent nerve growth factor regulation of Gs-alpha RNA in pheochromocytoma 12 cells.

نویسندگان

  • G Tjaden
  • A Aguanno
  • R Kumar
  • D Benincasa
  • R M Gubits
  • H Yu
  • K P Dolan
چکیده

Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (Gs-alpha) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density responded to NGF treatment with increased levels of Gs-alpha mRNA and protein. Conversely, in cells grown in low-density cultures, levels of this mRNA were lowered by NGF treatment.

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عنوان ژورنال:
  • Molecular and cellular biology

دوره 10 6  شماره 

صفحات  -

تاریخ انتشار 1990